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HomeLatest Pharma-NewsThe big twist on the largest clinical trial with Hydroxychloroquine

The big twist on the largest clinical trial with Hydroxychloroquine

June 03, 2020: The Lancet retracted the biggest study published regarding Hydroxychloroquine use for the treatment of COVID19.

“This study included all patients hospitalized at registry participating hospitals and with PCR-confirmed COVID-19 infection between Dec 20, 2019, and April 14, 2020, for whom a clinical outcome of either hospital discharge or death was recorded during hospitalization.”

96 032 hospitalized patients from 671 hospitals were infected with COVID-19 between 20 Dec 2019 and 14 April 2020 and fulfilled the requirements for inclusion in this report.

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The Lancet comments as “Important scientific questions have been raised about data reported in the paper by Mandeep Mehra et al—Hydroxychloroquine or chloroquine with or without a macrolide for treatment of COVID-19: a multinational registry analysis—published in The Lancet on May 22, 2020.

Although an independent audit of the provenance and validity of the data has been commissioned by the authors not affiliated with Surgisphere and is ongoing, with results expected very shortly, we are issuing an Expression of Concern to alert readers to the fact that serious scientific questions have been brought to our attention.”

https://www.thelancet.com/journals/lanpub/article/PIIS0140-6736(20)31290-3/fulltext

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