April 28, 2020: “In response to the novel coronavirus (SARS-CoV-2), Shionogi & Co., Ltd. has joined the ranks of pharmaceutical companies across the globe and is working with public institutions, academia and partner companies in the following efforts to fight against COVID-19:
- Commitment to the discovery of novel therapeutic drugs
Shionogi has initiated a collaborative research effort to identify drugs active against COVID-19 with the Hokkaido University Research Center for Zoonosis Control.
The research has identified a number of promising lead compounds from internal in vitro studies. As one of the top priorities for Shionogi, the company is accelerating drug discovery efforts with the aim of starting clinical trials later this year.
Shionogi is committed to the pursuit of effective compounds given the possibility of a long-lasting outbreak and pandemic. - Commitment to prophylactic vaccine development
UMN Pharma Inc., a group company of Shionogi, is pursuing the discovery and development of a recombinant protein vaccine for COVID-19 utilizing its unique Baculovirus Expression Vector System technology.
This project began in March 2020 and is supported by the Japan Agency for Medical Research and Development (AMED) [Representative of Research and Development: Dr. Hideki Hasegawa, Director of Influenza Virus Research Center, National Institute of Infectious Diseases].
Shionogi plans to start clinical trials in Japan within the year.
“Our key focus at Shionogi is to protect people from the threat and consequences of infectious diseases. We are not limiting ourselves to the research and development of therapeutic medications, but are also focused on the total care of infectious disease through awareness building, prevention and diagnosis,” said Akira Kato, Ph.D., president and CEO at Shionogi Inc.
“Shionogi will continue to strive to fulfill its social responsibility and to contribute to recovering the safety and security of society by bringing forward new tools and technologies for the treatment of COVID-19.”
Shionogi’s Commitment to Fighting Infectious Disease
Shionogi has a strong heritage in the field of anti-infectives and has been developing antimicrobial therapies for more than 50 years.
Shionogi is proud to be one of the few large pharmaceutical companies that continues to focus on research and development in anti-infectives.
The company invests the highest proportion of its pharmaceutical revenues in relevant anti-infectives R&D compared to other large pharmaceutical companies.
The company recently launched FETROJA® (cefiderocol) in the U.S. for patients 18 years of age or older who have limited or no alternative treatment options, for the treatment of complicated urinary tract infections, including pyelonephritis, caused by Gram-negative microorganisms.
Cefiderocol, under the brand name FETCROJA®, is approved by the European Commission for the treatment of infections due to aerobic Gram-negative bacteria in adults 18 years or older with limited treatment options.“
